Evaluation of Antifungal Effect of Silver Nanoparticles Against Microsporum canis, Trichophyton mentagrophytes and Microsporum gypseum
Authors
Abstract:
Background : Dermatophytosis is the common cutaneous infections in humans and animals, which is caused by the keratinophylic fungus called dermatophytes. In recent years , drug-resistance in pathogenic fungi, including dermatophytes to the current antifungal have been increased . The aim of this study was to evaluate the antifungal efficacy of AgNPs against Microsporum canis, Trichophyton mentagrophytes, and Microsporum gypseum. Materials and Methods: The antifungal susceptibility of nano-silver particles (AgNPs) compared with Griseofulvin (GR). Its efficacy was investigated against three strains of dermatophytes by both agar dilution and broth microdilution test (BMD). Results : The average minimum inhibitory concentration (MIC) of Ag-NPs on M. canis, T. mentagrophytes and M. gypseum were 200, 180, and 170 μg/ml , respectively. Whereas these strains showed MIC of 25, 100 and 50 μg/ml for Griseofulvin (GR). Conclusions: Our finding indicated that the AgNPs was less active than Griseofulvin (GR) but it had anti-dermatophytic effect.
similar resources
evaluation of antifungal effect of silver nanoparticles against microsporum canis, trichophyton mentagrophytes and microsporum gypseum
background : dermatophytosis is the common cutaneous infections in humans and animals, which is caused by the keratinophylic fungus called dermatophytes. in recent years , drug-resistance in pathogenic fungi, including dermatophytes to the current antifungal have been increased . the aim of this study was to evaluate the antifungal efficacy of agnps against microsporum canis, trichophyton menta...
full textDermatophytosis, Microsporum canis, Trichophyton mentagrophytes, Microsporum gypseum
Overview: The fungal skin disease dermatophytosis has come to be called ringworm because of the appearance of the skin lesion that characteristically occurs with this disorder: a circular area of hair loss with a red, raised outer rim. These lesions result from an inflammatory reaction to the fungus. Most often, dogs and cats are infected by the Microsporum canis fungus, but other types of fung...
full textExtracellular Production of Silver Nanoparticles by Using Three Common Species of Dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis
Background: To develop a new green approach for biosynthesis of silver nanoparticles, myconanotechnology has been represented as a novel field of study in nanotechnology. In this study, we have reported the extracellular synthesis of highly stable silver nanoparticles using three species of dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis. Methods: Clinical ...
full textIn Vitro Comparison of MIC Crude Extracts of Active Actinomycetes Isolated with Terbinafine, Griseofulvin Ketoconazole and Fluconazole against Microsporum Canis, Microsporum Gypseum and Trichophyton Mentagrophytes
Abstract Background and Objective: Dermatophytes are the fungi that have the ability to attack the keratinized tissues such as the skin, hair and nails. Infections caused by these organisms are named dermatophytosis. We aimed to compare Minimum inhibitory concentration (MIC) of Crude extracts of Active Actinomycete Isolates with Terbinafine, Griseofulvin, Ketoconazole and Fluconazole Drugs ...
full textExtracellular production of silver nanoparticles by using three common species of dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis.
BACKGROUND To develop a new green approach for biosynthesis of silver nanoparticles, myconanotechnology has been represented as a novel field of study in nanotechnology. In this study, we have reported the extracellular synthesis of highly stable silver nanoparticles using three species of dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes and Microsporum canis. METHODS Clinical ...
full textEvaluation of Antifungal Activity of Physalis alkekengi L. Extracts on Microsporum canis, Candida albicans, Trichophyton mentagrophytes and Nocardia asteroids
Physalis alkekengi L. has been used as anti-infective plant in Iranian traditional medicine. To investigate antifungal activity of the plant extract, wild plant was collected and identified and the aerial parts were air dried and powdered subsequently macerated in solvent. Extracts were concentrated by rotary evaporator at 60 C under reduced pressure. Aqueous, ethanol and methanol extracts were...
full textMy Resources
Journal title
volume 13 issue 4
pages 38- 42
publication date 2015-12-01
By following a journal you will be notified via email when a new issue of this journal is published.
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023